About the naming. This application is referred to in promotional material and in everyday speech by a brand name. Because the Turkish Regulation on Advertising and Information Activities in Health Services excludes the advertising of products and brands (Article 5/1-h) and the use of popular-culture names (Article 5/1-c), the clinical name is used on this page.
What is PRP?
PRP (platelet-rich plasma) is obtained from the person's own blood. The blood taken is separated by rapid spinning (centrifugation): first the red cells are separated, then the platelets are concentrated. The resulting plasma fraction, in which the concentration of platelets is higher than in circulating blood, is injected back.
Platelets are the cell fragments that start clotting in the blood. They do this through growth factors — these proteins can stimulate mesenchymal stem cells (cells able to turn into different tissues), which in turn can start, or restart, cellular production.
What is the aim in the genital area?
The reasoning on which the application rests is this: delivering the growth factors in the platelets to the clitoral area and to the Skene glands around the urinary tract.
The assumptions behind this:
- It is stated that the clitoris usually contains about 8,000 nerves, but that in many women this number is lower.
- The Skene glands produce a secretion during sexual activity; the amount varies from person to person, and in some women this secretion does not form at all.
- The aim is to stimulate the formation of new nerves in the clitoris and an increase in the secretion-producing cells in the Skene glands.
The starting point given for the application is the report in psychosexual studies that more than 10% of women have never experienced orgasm.
Where does the evidence stand today?
This section is the real purpose of the page. Everything below is the source's own wording; none of it has been added as criticism.
1. How long the results take to appear is not known
The source writes plainly: it is very difficult to say how long it will take for new nerve formation or an increase in secretion — and therefore for a change in sexual satisfaction — to appear.
2. Not everyone improves
In the authors' own practice, at 3 months about 10% of patients reported no improvement at all in their sexual satisfaction. The source also states that this datum is unpublished.
3. More studies are needed
The source states that in order for the results to be established more soundly, follow-up studies with larger numbers of patients and over longer periods are needed.
4. Even the existence of the target area is disputed
The G-spot, mentioned as one of the areas the application targets, was described in 1950. The source accepts that it is difficult to show whether this area is a real, identifiable anatomical structure present in every woman — because sexual arousal is an experience particular to the individual.
The scientific literature in the field is not one-sided either: while an anatomical study using ultrasound reported an area in the front wall of the vagina capable of producing orgasm, the same literature contains review articles describing the existence of this area as "a modern gynaecologic myth" and asking directly whether the G-spot exists.
5. The legal framework differs from country to country
The source states that the legislation governing PRP injection differs between countries and that in some places it is not permitted in the outpatient setting. It therefore notes that the application may not be an option everywhere.
What to do with this information
The above does not mean that the application "does not work". It means this: its effectiveness has not yet been established by large comparative studies, and part of the results reported rest on unpublished observations.
If you have a complaint relating to sexual function, the first step is not to choose a procedure but to have the cause of the complaint assessed. There may, for example, be genitourinary syndrome due to menopause, vaginal dryness, hormonal changes or other conditions causing pain; most of these have well-established treatments. Related pages: Genital Laser, Body-Identical Hormone Therapy.
You can consult your doctor about your own situation.
With any surgical procedure, results vary from person to person. You are advised to discuss the procedure with your doctor in detail beforehand.
Frequently Asked Questions
Why is no brand name used on this page?
The application is referred to in promotional material by a brand name. Because the Turkish Regulation on Advertising and Information Activities in Health Services excludes the advertising of products and brands (Article 5/1-h) and popular-culture names (Article 5/1-c), the clinical name is used on this page. The content describes the same application.
What is PRP and where does it come from?
PRP (platelet-rich plasma) is obtained from the person's own blood. The blood is separated by rapid spinning (centrifugation); first the red cells are separated, then the platelets are concentrated. Platelets contain growth factors able to stimulate mesenchymal stem cells (cells able to turn into different tissues); this is the reasoning on which the application rests.
What exactly does the application target?
The aim is to deliver the growth factors to the clitoral area and to the Skene glands around the urinary tract, in order to stimulate the formation of new nerves in the clitoris and an increase in the secretion-producing cells in the Skene glands. These are the intended mechanisms — it has not been shown in large studies that they actually occur.
When does the result appear?
The source gives no clear answer to this question: it states that it is very difficult to say how long it will take for new nerve formation or an increase in secretion, and therefore a change in sexual satisfaction, to appear.
Does it produce a result in everyone?
No. According to the report of the authors who perform the method, at 3 months about 10% of patients reported no improvement at all in their sexual satisfaction. The source also states plainly that this datum is unpublished.
What is the level of evidence for this method?
It is limited. In the source's own words, follow-up studies with larger numbers of patients and over longer periods are needed for the results to be established more soundly. In addition, whether one of the areas the application targets — the G-spot — is a real anatomical structure present in every woman is disputed in the literature; the same literature contains reviews describing it as "a modern gynaecologic myth".
Can it be performed in Türkiye?
The source states that the legislation governing PRP injection differs from country to country and that in some places it is not permitted in the outpatient setting. You need to consult your doctor about your own situation and the current legislation.
I have a complaint relating to sexual function — what should I do?
The first step is not to choose a procedure but to have the cause of the complaint assessed. There may be genitourinary syndrome due to menopause, vaginal dryness, hormonal changes or other conditions causing pain — most of these have well-established treatments. After assessment, the appropriate course is decided together.
Sources
- Catalisano C, Goisis M — Nanofat and injection applications in the G-spot area. In: Bader A (Ed.), Aesthetic Gynecology Rejuvenation. CRC Press, 2023, Chapter 13. Definition of the application, the mechanism on which it rests, the results reported by the authors, and the limits of the evidence they themselves state.
- Gräfenberg E — The role of the urethra in female orgasm. International Journal of Sexology 1950;3:145-148.
- Hines TM — The G-spot: A modern gynecologic myth. American Journal of Obstetrics and Gynecology 2001;185(2):359-362.
- Puppo V, Gruenwald I — Does the G-spot exist? A review of the current literature. International Urogynecology Journal 2012;23(12):1665-1669.
- Jannini EA, Buisson O, Rubio-Casillas A — Beyond the G-spot: Clitourethrovaginal complex anatomy in female orgasm. Nature Reviews Urology 2014;11(9):531-538.
The information on this page is based on the national and international guidelines listed above. The page is reviewed whenever those guidelines are updated.
Practice and Contact Details
The information on this page is general. Please speak to your doctor about your own situation.
- DoctorOp. Dr. Murat Alpay — Specialist in Obstetrics and Gynaecology
- AddressOp. Dr. Murat Alpay Practice, Tekelioğlu Cd. No:51 B Kat:2, Filo Apt., 07160 Muratpaşa / Antalya
- Telephone0505 351 77 88
- HoursMonday – Saturday 09:00 – 18:00 · Closed on Sunday