Genital PRP in female sexual function

Published: 30 June 2026 · Medically reviewed by: Op. Dr. Murat Alpay

What genital PRP is, which complaints it is considered for, how the procedure is carried out, what to avoid afterwards and when any effect becomes noticeable.

In consultations about women's health, sexual quality of life and difficulty reaching orgasm (anorgasmia) come up often — and are frequently assumed to have no solution. With the development of regenerative medicine, non-surgical approaches are now among the options used in managing female sexual dysfunction. One of these is genital PRP.

What genital PRP is

Genital PRP is the injection of platelet-rich plasma — obtained from the person's own blood — into specific points in the female genital area. The platelets in our blood, and the growth factors they release, play a key role in tissue repair and renewal.

The aim is to apply this plasma to areas important in sexual arousal, such as around the clitoris and the anterior wall of the vagina, and so support blood flow, the formation of new vessels (angiogenesis) and nerve stimulation in that area.

When it is considered

It is generally considered, after medical assessment, as a supporting method in women with the following complaints:

• difficulty with arousal during sex, or inability to reach orgasm (anorgasmia)
• numbness or reduced sensitivity in the genital area
• vaginal dryness related to the menopause or other hormonal change, and the painful sex (dyspareunia) that follows from it
• mild stress urinary incontinence

It is not performed in pregnancy or breastfeeding, in the presence of an active genital infection, or in patients with a bleeding or clotting disorder.

Is it painful, and how is it done?

Genital PRP is a non-surgical procedure carried out in a clinic setting, and it is comfortable. The steps are:

• a small amount of blood — about 15-20 ml — is taken from a vein in the arm and processed in a centrifuge to separate out the platelet-rich plasma;
• a local anaesthetic cream is applied to the genital area beforehand and left until the area is fully numb; where necessary, additional local anaesthetic can be given with very fine needles;
• the prepared plasma is injected with fine needles around the numbed clitoris and into the anterior wall of the vagina.

Because local anaesthesia is used, the procedure is generally well tolerated, and the whole process takes about 20-30 minutes.

Returning to daily life

One of the main advantages is that patients return to their normal day immediately afterwards. No admission or rest period is required.

Points to note afterwards:

• sex is not advised on the day of the procedure or for the first 24 hours; from the following day onwards it can resume;
• because PRP is intended to trigger a renewal process in the tissue, anti-inflammatory painkillers such as ibuprofen and aspirin are not advised for a few weeks afterwards. If pain relief is needed, a paracetamol-type medicine recommended by your doctor should be used instead;
• avoid very hot baths, saunas and heavy sport for the first few days;
• a light pinkish discharge, tenderness or a tingling sensation in the area during the first few days is entirely normal and settles on its own.

Because tissue renewal and collagen production take time, any positive effects generally begin to be noticed about 3 weeks after the procedure. Depending on the response, a repeat session may be planned in later months at the doctor's discretion.

See also genital PRP.