Op. Dr. Murat AlpaySpecialist in Obstetrics and Gynaecology 0505 351 77 88
Frequently Asked Questions

Gynaecological Conditions — Frequently Asked Questions

The questions under this subject are grouped by the page the answer comes from. For your own situation, please speak to your doctor.

Irregular and Abnormal Bleeding

How do I know whether my period is "heavy"?

Guidelines do not define this in millilitres. The criterion is this: is the bleeding adversely affecting your quality of life physically, emotionally, socially or materially? Not being able to go to work, hesitating to go out, having to change pads frequently and feeling constantly weak are meaningful indicators. There is no need to compare with someone else's bleeding.

I had a small amount of bleeding after menopause and it stopped. Should I still be seen?

Yes. Every episode of bleeding after menopause is a finding that needs to be investigated; its amount and duration do not change that. In 5 to 10 per cent of women with this bleeding the underlying cause is cancer of the womb, and early diagnosis changes the outcome markedly.

Is irregularity in adolescence normal?

Cycles without ovulation are common in adolescence, so a degree of irregularity is to be expected. But assessment is needed if the bleeding is excessive, produces symptoms of anaemia, or disrupts school and daily life; in that situation combined hormonal methods are recommended as first-line drug treatment.

Why is the hormonal coil the first thing recommended?

It is the option guidelines place first in heavy menstrual bleeding and in thickening of the lining of the womb in which the cell structure is not disturbed. Because it acts locally inside the womb, the amount of hormone that passes into the body is small, which reduces the side effects seen throughout the body. Even so, as with every method, its suitability is assessed for the individual.

Which test is done first for my irregular bleeding?

If you are of childbearing age, pregnancy is ruled out first. What follows depends on your age and the type of bleeding: after menopause, vaginal ultrasound comes first; before menopause, ultrasound is used mostly to look for structural causes such as fibroids and polyps. Anaemia is also looked for in everyone with abnormal bleeding.

Genital Warts Treatment

Do genital warts cause cancer?

The types that cause genital warts are the low-risk HPV 6 and 11. The types that cause cancers are different — most often 16 and 18. So having warts does not mean you are infected with a cancer-causing type. Even so, the screening recommendations should be followed.

How do they look, do they hurt?

They take the form of rounded bumps or plaques (raised patches) that may be skin-coloured, light and shiny, or dark grey, brown or purple; they are described as "cauliflower-like". They do not cause pain, but they may itch or become irritated.

What happens at the examination?

The diagnosis is mostly made by examination. 3–5% acetic acid may be applied as an aid — it makes mucosal cells (the thin tissue lining the inner surface) infected with HPV turn white and so visible. HPV DNA can also be looked for by PCR in the samples taken. Because there are other conditions that look like warts (skin tags, moles, seborrhoeic keratosis, molluscum, condylomata lata and some skin cancers), assessment is necessary.

Do condoms protect against it?

Partly. Used correctly and consistently they are quite effective, but they do not give complete protection: HPV can also be transmitted by skin-to-skin contact and from areas outside the barrier. It has also been documented that HPV can be transmitted without sexual intercourse — through intermediate objects such as clothing, medical equipment and surfaces, and through non-sexual skin contact.

Which treatment is right for me?

There are two families. Tissue-destroying procedures: freezing (cryotherapy), cautery, surgical removal and laser vaporisation. Topical treatments: podofilox and imiquimod (which you apply yourself) and sinecatechin ointment (applied by the doctor). The choice is made according to the site, size and extent of the warts. Surgical removal, for example, provides tissue for pathological examination, while laser is useful for widespread lesions (tissue changes) that are difficult to reach.

Do they come back after treatment?

Yes, recurrence is common and most people need more than one treatment session. This does not mean the treatment has not worked — it is the nature of the condition. Using tissue-destroying and topical methods together can increase clearance and reduce recurrence, particularly in widespread disease.

Is treatment with laser or cautery safe?

These heat-based methods can release virus particles into the air, and this carries a possible risk of warts forming in the throat. For this reason an appropriate respirator mask and a surgical smoke extractor need to be used during the procedure. That is why it matters that the procedure be carried out in a properly equipped setting.

Will my immune system clear the warts on its own?

HPV infection is mostly cleared by the immune system. But in people whose immune system is suppressed — those with systemic lupus (affecting the whole body), HIV infection or a history of organ transplant — the risk of the infection persisting is higher. Tobacco use is also among the factors that increase the risk.

Hysteroscopy

Is hysteroscopy done only to look?

No. It is direct visualisation of the inside of the womb with a fine telescope, but treatment can also be carried out in the same session — this is called the "see and treat" approach. Removing polyps and fibroids, dividing adhesions, cutting a septum, removing a lost coil and removing pregnancy tissue remaining in the womb can all be done this way.

Which method is better for removing a polyp?

The guideline prefers mechanical tissue-removal systems to small electrical tips, and recommends this at the highest level of evidence. In a comparative study the mechanical system was found to be less painful, faster and to have a higher success rate.

Do adhesions come back after they are divided?

This is a real risk, because surgery on the womb is itself a cause of adhesions. For this reason treatment does not end with dividing the existing adhesion; protective measures such as barrier gels containing hyaluronic acid, absorbable medical membranes or an intrauterine device must be used to prevent a new one from forming.

Does an operation for a uterine septum reduce my risk of miscarriage?

In people who have experienced recurrent pregnancy loss, correction of the septum with hysteroscopy is reported to reduce the rates of pregnancy loss markedly. Mechanical mini-scissors that use no electricity are preferred in the procedure; they are significantly less painful than electrical tips.

Do I need to take an antibiotic before the procedure?

No, routine preventive antibiotics are not recommended. In a large randomised study no significant difference was found in the infection rate between those given antibiotics and those not given them (1.0% versus 1.3%). The exception: if an active infection is suspected before the procedure it is postponed and treated; if pus is found in the womb during the procedure, intravenous antibiotics are started immediately.

Can my womb be perforated?

It is rare but serious; the reported rate is between 0.002% and 1.7%. In a diagnostic procedure it is less than one in a thousand, and a little more frequent when a polyp or fibroid is removed. Factors that increase the risk: the need to dilate the cervix by more than 6 mm, narrowing of the cervix, a tortuous canal and an excessively angled womb.

Will I faint during the procedure?

Fainting, nausea and dizziness can occur: reported at 1.1% in a diagnostic procedure and at 5.8–12% in treatment procedures such as polyp and fibroid removal. Using salt water instead of carbon dioxide to distend the inside of the womb reduces this reaction significantly.

How long does it take and what should I do afterwards?

It generally takes 10–15 minutes; it may take longer if an additional procedure is carried out. Taking a painkiller 1–2 hours before the appointment is recommended. Afterwards use a pad, not a tampon. Bleeding for a few days that is lighter than a period is normal.

When should I seek help without delay?

If you have abdominal pain that does not settle with a simple painkiller, bleeding heavier than a period, or signs of infection such as fever, shivering and foul-smelling discharge, seek help without delay. You should be given telephone numbers you can reach, including an out-of-hours number.

If I cannot bear it, will the procedure be stopped?

Yes. The procedure can be stopped at any moment. If pain or discomfort becomes unbearable, telling the team is enough; the procedure is stopped immediately. The team is also obliged to take into account that you may not be in a position to say so.

HPV (Human Papillomavirus)

Does HPV turn into cancer?

HPV itself is not cancer. In about 90% of people the virus clears on its own within 1–2 years. Only when a high-risk type becomes persistent can changes begin in the cells of the cervix; these usually take 15–20 years to turn into cancer. Regular screening catches these changes before they turn into cancer.

Does HPV go away on its own?

Mostly, yes. According to the World Health Organization, in about 90% of people the immune system controls the infection on its own and the virus is usually cleared within 1–2 years. Stopping smoking reduces the chance that the virus becomes persistent.

My HPV test is positive — what should I do?

A positive HPV test does not mean you have cancer. The next step is decided by the type found and by the cell examination: if HPV 16 or 18 was found, or if the cells show a change, a colposcopy (examination of the cervix under magnification) is done; with other types, if the cell examination is normal, the test is usually repeated after a certain time (most often 1 year). Please consult your doctor about what your own result means.

How is HPV passed on, and do condoms protect?

HPV is passed on through sexual contact and skin-to-skin contact; transmission outside sexual intercourse has also been documented. Condoms reduce the risk but do not give full protection, because they do not cover all of the skin in the genital area. The most effective way of protection is vaccination.

Is there a treatment for HPV?

There is no medicine that removes the HPV infection itself; most of the time the body clears the virus. What is treated are the problems HPV causes: genital warts (freezing, cautery, surgery, laser, medicines applied to the skin) and precancerous changes in the cervix (destroying them, or removing them with small surgical procedures such as LEEP).

Up to what age can the HPV vaccine be given?

It is most effective at ages 9–14, before sexual life begins. It is recommended up to the age of 26 for people who have not been adequately vaccinated; between 27 and 45 it may be considered through a decision made together with the doctor. The vaccine is not recommended in pregnancy; it is postponed until after the pregnancy.

If I have had the HPV vaccine, do I still need screening?

Yes. The vaccine protects against the types that most often cause cancer, but it does not replace screening. People who have been vaccinated should also follow the screening recommendations for their age.

At what age is HPV screening done in Türkiye?

The Turkish Ministry of Health national cervical cancer screening programme offers an HPV-DNA test every 5 years to women aged 30–65. Follow-up for people with a previous abnormal result or whose immune system is suppressed is planned separately.

Urinary Incontinence

Do I need an operation straight away for my incontinence?

No. Guidelines recommend treatments without medicines as the first step: in the stress and mixed types, supervised pelvic floor muscle training for at least 3 months; in the urge and mixed types, bladder training for at least 6 weeks. Surgery comes up after these and, where appropriate, drug treatment have been tried.

How should I do the pelvic floor exercise?

The programme should last at least 3 months, be supervised and include at least 8 contractions three times a day. Before starting, an examination is done to confirm that you can contract the muscles correctly — this step matters, because exercising the wrong muscle produces no result. Devices that show muscle activity on a screen are not routinely recommended.

Which tests are unnecessary?

At the first assessment, the Q-tip, Bonney and Marshall tests, and routine cystoscopy (examination of the bladder with a camera) and imaging methods (MRI, CT, X-ray) should not be used. What is needed: a detailed history, a urine dipstick test, an examination, a bladder diary for at least 3 days and, if necessary, measurement of the amount left after passing urine by ultrasound.

Is bladder pressure measurement (urodynamic testing) essential before an operation?

No. In people in whom the history and examination clearly identify the stress type or a stress-predominant mixed type, routine urodynamic testing before a first operation is not recommended. The situations in which it is needed: urge-predominant mixed type or uncertainty about the type, suspicion of difficulty emptying the bladder, accompanying pelvic organ prolapse, and a previous unsuccessful operation for stress incontinence (urinary leaking).

If I start a medicine, will it improve straight away?

No, patience is needed. With medicines that relax the bladder (anticholinergics), at least 4 weeks are needed for the full benefit. Side effects such as dry mouth and constipation may indicate that the medicine is working. It should also be explained to you that the long-term effects on cognitive function are uncertain.

I am in menopause — will hormone treatment help my incontinence?

Hormone treatment that affects the whole body (systemic) has no place in the treatment of urinary incontinence. But if you have complaints such as dryness, painful intercourse and irritation due to menopause and also have an overactive bladder, local (vaginal) oestrogen should be offered. These two are different things.

I get up often at night to pass urine — is there anything for that?

Desmopressin may be considered for getting up at night where this affects your quality of life. But care is needed in patients with cystic fibrosis, and it should be avoided in those over 65 and those with cardiovascular disease.

Does losing weight really help?

The guideline recommends weight loss for women with a body mass index above 30. It also recommends reducing caffeine in overactive bladder, and fluid intake is adjusted if it is very high or very low.

Colposcopy

Why has colposcopy been requested — does it mean I have cancer?

No. Colposcopy is done not because a diagnosis of cancer has been made but to measure risk. Guidelines define colposcopy as a risk assessment tool: it guides whether treatment, biopsy or only follow-up is needed afterwards. Being able to show safely that there is no disease is also one of the benefits colposcopy provides.

Is colposcopy painful, and how long does it take?

Colposcopy usually takes 15–20 minutes. There may be mild discomfort while the speculum is put in, mild tingling or stinging while the liquid is applied and, if a biopsy is taken, a slight pinching feeling. Some people may find it painful; you can ask for the procedure to be stopped at any moment.

What should I pay attention to before colposcopy?

In the 24 hours before the procedure, do not have vaginal intercourse; do not use tampons, vaginal creams or medicines. If you use a coil, avoid intercourse or use a condom in the 7 days before. If you are pregnant or think you may be, say so beforehand.

Can colposcopy be done during my period?

Yes, it can also be done during your period. If you prefer, you can change your appointment to after your period has ended.

When can I have intercourse after a biopsy?

For as long as the bleeding and discharge continue, it is recommended that you do not have intercourse or use tampons. If only a biopsy was taken, this is usually a few days; if LEEP was done, you may be asked to avoid intercourse for 4 weeks.

What do CIN 1, CIN 2 and CIN 3 mean?

CIN is a precancerous cell change in the surface layer of the cervix; it is not cancer. CIN 1 is low grade and is usually followed up; CIN 2 may be followed up or treated; CIN 3 is high grade and removal of the changed tissue is recommended.

Can colposcopy be done in pregnancy?

Yes, colposcopy can also be done safely in pregnancy. Be sure to mention that you are pregnant before the procedure.

What is applied to the cervix during the procedure?

First acetic acid at a concentration of 3–5% is applied; this is a dilute vinegar solution and makes suspicious areas turn white temporarily. Where necessary, Lugol's iodine solution is also used to see whether the tissue takes up the stain. These two applications guide the taking of the biopsy from the right point.

Is a biopsy always taken at colposcopy?

Not always. In low-risk people whose colposcopic appearance is normal, not taking a biopsy is an acceptable approach. When a suspicious area is seen, targeted biopsies are generally taken from 2 to 4 points so that the most advanced change is not missed.

Is the colposcopy result a definitive diagnosis?

No. The colposcopic impression is a visual assessment and is not accepted as definitive on its own; for this reason it is recommended that suspicious areas be sampled by biopsy. The definitive diagnosis is made by the pathology (tissue) examination of the biopsy.

Can treatment also be carried out during colposcopy?

In selected situations, yes. In high-risk people with strong evidence in favour of high-grade disease, removal of the transformation zone with a loop may be done immediately after the colposcopy, so that diagnosis and treatment take place in the same session. This is not a practice that applies to everyone; your own findings determine the decision.

Is colposcopy used only for the cervix?

Colposcopy has other uses as well, such as assessment of the vagina and the vulva. But what is described on this page is colposcopic assessment within the scope of preventing cervical cancer.

Laparoscopic (Keyhole) Surgery

What is the advantage of keyhole surgery over open surgery?

There is less pain and less need for painkillers after the operation, the hospital stay is shorter and the return to work is faster. Wound infection is less frequent, there is less blood loss and the scar is very small. One of the most important: fewer adhesions form — which is particularly valuable for those thinking of a pregnancy later.

How risky is it?

The great majority pass without problems. In diagnostic laparoscopy the risk of a serious complication is about two in a thousand. Bowel injury is 0.4–1.1 in a thousand; major vessel injury 0.1–0.2 in a thousand; injury to the bladder or urinary tract 0.3 in a thousand. Death is very rare (3–8 in a hundred thousand). The risks increase if an additional treatment procedure is carried out.

What should I watch for at home after the operation?

This is very important: about 15% of bowel injuries cannot be noticed during the operation and show themselves days later, often after you have been discharged. Increasing abdominal pain — particularly if accompanied by fever, loss of appetite and vomiting — means you should seek help without delay.

For which symptoms should I call for emergency help?

Shortness of breath, chest pain or coughing up blood — this may indicate that a clot has travelled to the lung; call for emergency help. Pain, redness, swelling or warmth in the leg, or difficulty putting weight on it, may also be a sign of a clot in a vein. Redness and pain around the scars suggest a wound infection.

Why does my shoulder hurt?

This is expected and temporary: part of the gas used to inflate the abdomen during the operation remains behind and irritates the diaphragm, causing pain at the tip of the shoulder. Similarly, trapped wind can occur because the bowels slow down temporarily; walking relieves it.

How can I reduce the risk of a clot?

Move as early as possible. Even while resting, move your ankle and pump each foot briskly up and down for 30 seconds. Also take your painkiller regularly — if the pain is under control you will get up earlier, which both speeds up healing and prevents clots.

I have had abdominal surgery before — will that be a problem?

This is assessed beforehand. The rate of adhesions around the navel can be as high as 50% after a midline incision and 23% after a low transverse incision. For this reason the surgeon may prefer to make the entry at a different point. Excess weight and being very thin also affect the entry plan.

Why is being very thin considered a risk?

Because when the abdominal wall is thin, the deep structures come very close to the skin. In young, very thin women with well-developed abdominal muscles who have never given birth in particular, the main artery may be only 2.5 cm below the skin. Because this is known, the entry method is chosen accordingly in this group.

Can an operation start as keyhole and become open?

Yes, this is a known possibility and it should be explained to you before the operation. It is also part of the information given that laparoscopy (viewing the abdomen with a camera) may not find the cause of your complaint.

LEEP

What is the difference between LEEP and a biopsy?

A biopsy takes a small piece in order to make a diagnosis. LEEP removes the whole transformation zone; that is, it both treats and provides pathology with a complete tissue sample. That sample makes it possible to see whether there is a more advanced change than expected and whether the surgical margins are clear.

I have CIN 2 — do I have to have an operation?

As a rule treatment is recommended for CIN 2; but follow-up can also come up — if your concerns about the effect of treatment on future pregnancies outweigh your concern about cancer. This is a matter for shared decision making. There are also situations in which follow-up is not accepted: if the upper border of the transformation zone cannot be seen, or if the sample taken from the canal shows CIN 2 or above. With CIN 3, follow-up is not accepted in those who are not pregnant.

Which is better, LEEP or freezing (cryotherapy)?

Guidelines prefer removal methods for high-grade changes — but the reason is not a definite superiority in success. A Cochrane review comparing the surgical techniques concluded that no technique is clearly superior in terms of treatment failure or side effects. What LEEP actually provides is a tissue sample to send to pathology and information about the surgical margins; with burning methods this information cannot be obtained.

Can I be treated with a cream applied to the cervix, or with a vaccine?

No. For high-grade cell changes, topical medicines, therapeutic vaccines and similar non-surgical methods are not acceptable outside the setting of a clinical trial. This is what the guidelines state plainly.

Can LEEP be done without a biopsy first?

In some situations, yes; this is called expedited treatment. The decision depends on the current risk of CIN 3 or worse: if the risk is 60% or more, direct treatment is preferred; in the 25–59% range both direct treatment and colposcopy with biopsy first are acceptable. This decision should be taken together with your doctor, particularly if you are planning a pregnancy.

Why does the size of the tissue removed matter?

In glandular cell change in the cervical canal (AIS), removing the piece in one piece is preferred so that the margins can be interpreted correctly. A length of at least 10 mm is preferred; in those who have no concerns about the effect on future pregnancies it can be increased to 18–20 mm. Deliberately dividing the piece is not acceptable.

I have CIN 1 — is treatment needed straight away?

Generally no. CIN 1 is the appearance of HPV infection in the tissue and the rate of it regressing on its own is high, particularly at younger ages. Even in those aged 25 and over in whom CIN 1 has been found for at least two years in succession, follow-up is preferred; treatment is an acceptable option only as a personal preference after shared decision making.

Uterine Fibroids

Can fibroids cause cancer?

Fibroids are almost always non-cancerous, and an existing fibroid is not expected to turn into cancer. The very rare muscle cancer of the womb (leiomyosarcoma) usually develops as a separate tumour, independent of fibroids. In operations done for presumed fibroids, this cancer has been found unexpectedly in about 1 in 400 to 1 in 1000 operations. A fibroid that grows after the menopause should be assessed in detail.

Does every fibroid need treatment?

No. For fibroids that cause no complaints and raise no suspicion of cancer, no surgery or medicine is needed. Keeping track of symptoms, regular gynaecological examinations and usually a yearly ultrasound check are enough.

Can fibroids be treated without surgery?

Depending on the complaint, yes. Medicines that reduce bleeding (hormonal coil, medicines that stop clots from breaking down too early, contraceptive pills) and hormone-suppressing medicines that shrink the fibroid temporarily can be used; however, medicines do not remove fibroids. In women not planning a pregnancy, uterine artery embolisation, and focused ultrasound or heat-based shrinking, are counted among the womb-sparing options.

What size of fibroid needs surgery?

The decision on surgery is not made on the size in centimetres alone. What matters is the complaint the fibroid causes (heavy bleeding, anaemia, pressure, difficulty becoming pregnant), its position, the woman's age and her wish for children. A fibroid causing no symptoms can be monitored, while a small fibroid growing into the cavity of the womb may be removed because of bleeding or pregnancy problems.

Do fibroids prevent pregnancy?

Not every fibroid does. Fibroids that distort the cavity of the womb and large fibroids in the muscle wall can make it harder to become pregnant and have been linked with miscarriage and premature birth. Removing fibroids that grow into the cavity of the womb by hysteroscopy has been reported to increase pregnancy and live birth rates. A decision is made after assessing your situation with ultrasound.

How soon after fibroid surgery can I become pregnant?

After a myomectomy it is usually recommended to postpone pregnancy for 3 to 6 months so that the wall of the womb can heal. If the muscle of the womb was cut deeply or the cavity of the womb was entered, birth by caesarean section is recommended.

Do fibroids come back after surgery?

In a myomectomy only the fibroids are removed and the womb is kept, so new fibroids can develop in other parts of the womb. The only method that completely removes the risk of recurrence is removal of the womb (hysterectomy); pregnancy is not possible after this method.

Do fibroids shrink after the menopause?

Usually, yes. The growth of fibroids depends on the hormones oestrogen and progesterone; because these hormones fall at the menopause, fibroids usually shrink and complaints ease. A fibroid that grows after the menopause, or new bleeding, is unusual and should be assessed.

What symptoms do fibroids cause?

Most women with fibroids have no symptoms. When there are symptoms, the most common is heavy, long or clotty periods; anaemia and tiredness can develop as a result. Large fibroids can cause fullness in the abdomen, frequent urination or constipation.

How are fibroids detected?

The first step in diagnosis is ultrasound; this shows the number, size and position of the fibroids. When needed, a more detailed assessment is made with saline ultrasound, MRI or hysteroscopy (looking inside the womb with a camera).

Smear and HPV Testing

Should I have a smear or an HPV test?

The HPV test is more sensitive and, when negative, gives stronger reassurance that there is no cancer. For this reason screening with the HPV test alone (primary HPV screening) has become the preferred method in guidelines. A smear looks at cells, while an HPV test looks for the presence of the virus that can lead to cancer.

At what age does screening start and how often is it done?

According to the American Cancer Society guideline, primary HPV screening is the preferred method, to be done every 5 years from the age of 25. If the sample was taken by a doctor and the result is negative, it is repeated every 5 years. National screening programmes differ between countries; ask your doctor about your own plan.

Can I collect the sample myself?

Yes, this is now an approved option and does not require an examination instrument (speculum). But a sample taken by a doctor is preferred; a self-collected sample is considered acceptable for people aged 25–65 at average risk. An important difference: if a test on a self-collected sample is negative, the repeat interval is not 5 years but 3 years. In some higher-risk people a doctor-taken sample continues to be recommended.

My HPV test is positive — do I have cancer?

No. An HPV test is not a cancer test; it shows the presence of the virus that can lead to cancer. Most of those whose test is positive need further assessment steps — this usually means examination of the cells and, where necessary, Colposcopy. Your findings determine the next step.

When can I stop screening?

For screening to be brought to an end in a person at average risk, the HPV tests done at ages 60 and 65 must be negative; it is a condition that the last HPV test not be at an age younger than 65. If these tests are not available, three consecutive negative examinations of the cells done at the recommended interval, the last of them at the age of 65, is acceptable.

At what age should the HPV vaccine be given?

It is recommended routinely at age 11 or 12 and can be started from the age of 9. The American Cancer Society encourages recommending it from the age of 9 or 10, because the vaccine is more effective at younger ages — being vaccinated at 12–13 is markedly more effective than at 14–15.

I am over 26 — is it worth being vaccinated?

It is recommended up to the age of 26 for everyone who has not been adequately vaccinated. Between 27 and 45 it may be considered through a shared decision with the doctor; but it is stated that most adults in this age group will not benefit from the vaccine. The vaccine is not licensed for those over 45.

Do I need an HPV test before being vaccinated?

No. Doing a smear or HPV test before vaccination in order to decide whether the vaccine is appropriate is not recommended. The recommendations apply to everyone, regardless of behavioural or medical risk factors for HPV.

I have been vaccinated — can I skip screening now?

No. The vaccine does not take the place of screening. People who have been vaccinated also need to continue following the cervical cancer screening recommendations.

I am pregnant or breastfeeding — can I be vaccinated?

In pregnancy HPV vaccination is postponed until after the pregnancy; but there is no need for a pregnancy test before vaccination. People who are breastfeeding can be vaccinated.

Polycystic Ovary Syndrome

Is an ultrasound essential for a diagnosis of PCOS?

No. In an adult woman with both irregular periods and excess male hormone, two of the three criteria are already met — there is no need for an ultrasound or an AMH test. An ultrasound is needed only if just one of these two findings is present, in order to assess the third criterion.

My daughter was told she has PCOS and had an ultrasound — is that right?

In young girls within the first 8 years after their first period, the use of ultrasound and AMH is not recommended. The reason is this: having many small follicles in the ovaries can be normal at this stage, and looking at an ultrasound leads to unnecessary diagnoses. In this age group, excess male hormone and irregular periods must be present together for the diagnosis.

Is there a special diet for PCOS?

The guideline states plainly: there is no single diet or exercise programme specific to PCOS. The general principles of healthy eating apply, and the form you can keep up and prefer yourself should be chosen. Approaches claiming that "this diet solves PCOS" have no counterpart in the guideline.

What treatment is used for my excess hair growth?

The first step is contraceptive pills; they are also the first option for irregular periods and acne. If an adequate response is not obtained from these or from cosmetic methods for at least 6 months, anti-androgen medicines are considered. Laser and light-based treatments are also effective in reducing unwanted hair.

What should I be careful about while taking an anti-androgen medicine?

You must use a highly effective method of contraception. These medicines can cause a developmental problem in a male baby. For this reason contraception must not be neglected during treatment.

Which screening tests should I have?

Everyone at diagnosis — regardless of age and weight — should have fasting blood lipids checked and their blood sugar situation assessed. Blood pressure is measured every year. Lipid and sugar screening is repeated every 1–3 years if there are risk factors. The most sensitive test for sugar is the glucose tolerance test.

Am I at risk of cancer of the womb, should I be screened by ultrasound?

In premenopausal women with PCOS the risk is increased 2- to 6-fold, but the actual risk is still low. Routine screening of thickness by ultrasound is not recommended. However, if you have not had periods for a long time, have abnormal bleeding or have risk factors such as excess weight, the threshold for investigation is kept low. The way to protect against it: weight management, establishing a regular menstrual cycle and regular progesterone treatment.

I am planning a pregnancy — what should I do?

PCOS is regarded as high risk in pregnancy. When planning a pregnancy, blood pressure should be measured and a glucose tolerance test done. If this was not done beforehand it is done at the first antenatal visit and then repeated at weeks 24–28.

Does PCOS affect my mood?

Yes, and this should not be overlooked. Anxiety, low mood, sleep disturbance and eating disorders are markedly more common in PCOS. Sleep apnoea is also more common; if there is snoring and excessive daytime sleepiness, it should be assessed.

Who else in my family is at risk?

Metabolic syndrome, type 2 diabetes and high blood pressure are more common in the fathers and brothers of women with PCOS. This means family members should not neglect their own check-ups either.

Endometrial Polyps

Can a polyp in the lining of the womb (endometrial polyp) turn into cancer?

Most polyps are benign (not cancer). Before the menopause, the risk of finding cancer or a precancerous change inside a polyp is about 1–2%; after the menopause it is clearly higher, at 3–13% (on average 5.4%). In polyps that bleed the risk is about 4.5–5.1%, and in polyps that never bleed and are found by chance it is 0.2–1.5%. Being over 60, a polyp larger than 1.5 cm and use of tamoxifen increase the risk.

Does a polyp go away on its own?

Small polyps without symptoms can disappear on their own. Follow-up studies have reported that about 27% of polyps without symptoms disappear within a year, and that this rate rises to 50% for those smaller than 1 cm. For this reason, in women before the menopause who have no complaints and a small polyp, an ultrasound check every 6–12 months may be an option.

How is polyp surgery done, and how long does it take?

The polyp is removed by hysteroscopy (viewing the inside of the womb with a camera); no cut is made in the abdomen. The cervix is gently widened, and the polyp is seen with the camera, cut together with its root and removed. The time depends on the size and number of polyps. Most women go home the same day and can return to daily life within 1–2 days.

Is general anaesthesia needed to remove a polyp?

Not always. Small, single polyps can be removed as an outpatient without general anaesthesia, with light local numbing or without any numbing. For large or multiple polyps, or when the cervix is narrow, the procedure is done in the operating theatre under light sedation or general anaesthesia.

Does a polyp prevent pregnancy?

It can. A polyp is found in about 15–32% of women being assessed for infertility. A polyp can disturb the surface where the embryo attaches, make it harder for sperm to move forward or block the openings of the tubes. In one study the pregnancy rate was higher in women whose polyp was removed before insemination (51% versus 28%). ESHRE and ASRM guidelines recommend removing the polyp before IVF. Results can vary from person to person.

What is done if a polyp is found after the menopause?

Because the risk of cancer or a precancerous change is higher in polyps found after the menopause, removal of all polyps found in this period is recommended. Polyps are responsible for about 25–38% of bleeding after the menopause.

What symptoms does a polyp cause?

Between 12% and 50% of polyps cause no symptoms at all. When there are symptoms, the most common are spotting or bleeding between periods, heavier or longer periods, bleeding after sex and bleeding after the menopause. Less often, cramps, period pain or discharge may occur.

Can a polyp be seen on ultrasound?

Yes. Ultrasound done through the vagina is the first-step examination. Ultrasound done after saline is placed inside the womb shows the size and stalk of the polyp with a sensitivity of 88–95%. A definite diagnosis, and the chance of removal in the same session, are provided by hysteroscopy.

Does a polyp come back after it has been removed?

For polyps removed completely under direct vision together with their root, the risk of coming back is under 5%. The root not being fully cleared, or hormonal factors such as oestrogen dominance or tamoxifen use continuing, increase the likelihood of recurrence.

Vaginal Discharge

Is it normal to have discharge?

Yes, there is discharge in the vagina normally too. Normal discharge is small in amount, clear or white and has no smell; it is not accompanied by itching, burning or irritation. It is also normal for it to increase temporarily and become more watery in the middle of the menstrual cycle (at ovulation).

My discharge has a smell — what does that mean?

The smell is an important clue. A fishy smell — particularly if it becomes more noticeable after intercourse and during the period — suggests bacterial vaginosis. In thrush there is no smell. In trichomoniasis an unpleasant smell is seen together with frothy, yellow-green discharge.

My itching is very bad — is it thrush?

Severe itching is the most typical feature of thrush; it is seen together with burning, irritation, swelling and redness of the external area, and the discharge is in clumps like cottage cheese. In bacterial vaginosis, by contrast, because there is no true inflammation, marked itching is generally not seen. Even so, the definite distinction is made by examination.

Can't I just buy a thrush treatment at the pharmacy?

That is a risky route: according to the sources, more than half of the diagnoses people make themselves are wrong. The three conditions produce similar complaints but their treatments are completely different. Also, no response within 3 days to a medicine bought without prescription, or immediate recurrence, may point to a resistant species.

What happens at the examination?

Simple and quick steps: the appearance of the discharge is assessed, the acidity (pH) is measured, a smell test is done and a sample is examined under the microscope. These few steps are enough to tell the three conditions apart. Because the detection power of the microscope is limited in trichomoniasis (51–70%), molecular testing may be preferred.

Should I have a culture for bacterial vaginosis?

No. Bacterial culture has no place in this diagnosis — because the bacterium held responsible can be found in the normal flora of 50–60% of healthy women as well. The diagnosis is made by assessing certain criteria together.

Does my partner need treatment too?

That depends on the organism. In bacterial vaginosis treating the partner is not recommended — it has been shown not to reduce recurrence. In thrush it is not routinely recommended either. But in trichomoniasis it is essential: because it is transmitted sexually, partners need to be treated at the same time whether or not they have symptoms, and sexual contact should be avoided until the treatment is finished.

I am pregnant and have discharge — can it wait?

No, seek help without delay. Bacterial vaginosis and trichomoniasis during pregnancy can lead to the waters breaking early, premature birth and low birth weight.

Should I douche?

No. Although it may look like cleaning, it removes the protective Lactobacillus bacteria, disturbs the natural acid balance of the vagina and prepares the ground for infection. Antibiotic use and hormonal changes are also among the factors that can disturb this balance.

I am in menopause and discharge has started — does it matter?

Yes. Any vaginal discharge that starts after menopause must be investigated. It may be due to thinning of the tissues, but other causes need to be ruled out as well.

Vaginal Infection Treatment

How can thrush be told apart from bacterial vaginosis?

In thrush the discharge is thick, white and looks like cottage cheese, usually has no smell, and severe itching is to the fore. In bacterial vaginosis the discharge is thin and grey-white, there is a fishy smell, and itching is usually absent. Even so, the definite distinction is made at the examination by measuring the pH (level of acidity) and looking under the microscope.

Is bacterial vaginosis sexually transmitted?

It is not considered a classic sexually transmitted infection; it can also occur in women who have never had sex. Even so, a new partner or more than one partner and unprotected sex increase the risk. Treating the male partner is not recommended.

Can thrush pass to my partner, and does he need treatment too?

Vaginal thrush is not a sexually transmitted infection, and partner treatment is not routinely recommended. Only if the male partner has symptoms of balanitis (redness and itching of the head of the penis) is a local antifungal cream recommended for him too.

Why is partner treatment essential in trichomoniasis?

Trichomoniasis is a sexually transmitted infection. If the partner is not treated, the infection is passed on again. This is why partners are treated at the same time, even if they have no symptoms, and sex is avoided until the treatment has been completed and the symptoms have gone.

Can trichomoniasis be treated with a vaginal gel?

No. According to the guidelines, vaginal metronidazole gel is not adequate for treating trichomoniasis. Treatment is with medicines from the nitroimidazole group (antibiotics that work against parasites) taken by mouth.

Can I buy a thrush cream from the pharmacy and use it?

The diagnoses people make themselves are wrong in more than half of cases. If the symptoms are actually due to bacterial vaginosis or trichomoniasis, a thrush cream will not work, delays the diagnosis and can upset the balance of the vagina even further. If the symptoms are happening for the first time, or do not go away with over-the-counter medicine, a doctor's assessment is needed.

My thrush keeps coming back — what can be done?

With 4 or more episodes a year, it is considered recurrent thrush. A culture is done to identify the species responsible. In treatment the infection is first brought under control, then a maintenance (continuing) treatment lasting several months is given. For resistant species, other options are considered.

Why does bacterial vaginosis come back after treatment?

After treatment, bacterial vaginosis can come back within 3 months in about 30% of women. When it keeps recurring, a suppressive treatment lasting several months or a switch to a different group of antibiotics may be planned. Avoiding douching and perfumed products helps to protect the balance.

Are vaginal infections treated in pregnancy?

Yes, but the choice of medicine changes. In pregnancy, bacterial vaginosis and trichomoniasis are linked to a risk of premature birth. For thrush, antifungal medicines taken by mouth are avoided and vaginal creams and pessaries are preferred. Medicines should not be self-prescribed in pregnancy.

Do probiotics cure a vaginal infection?

The use of probiotics containing Lactobacillus to support treatment or to prevent recurrence is being studied. However, current guidelines do not yet have enough evidence that they can replace antibiotic or antifungal treatment.

Ovarian Cysts

Does an ovarian cyst go away on its own?

Most functional (temporary) cysts do. Before the menopause, cysts that look simple on ultrasound and are smaller than 5 cm usually disappear on their own within 1–3 menstrual cycles. Yellow body cysts in early pregnancy also usually shrink by the second three months. For other types, such as chocolate cysts, dermoid cysts and cystadenomas, a separate monitoring or treatment plan is made.

What size of ovarian cyst needs surgery?

The decision is not based on size alone. Before the menopause, among cysts with a simple appearance, those under 5 cm usually disappear on their own, and those between 5 and 7 cm can be monitored with a yearly ultrasound; for persistent cysts larger than 7 cm, surgery is considered. Regardless of size, growing cysts, suspicious ultrasound findings, severe pain, and emergencies such as twisting of the ovary or a burst cyst are also reasons for surgery.

Does a chocolate cyst cause infertility?

A chocolate cyst (endometrioma) can damage ovarian tissue and lower the ovarian reserve (the remaining store of eggs); removing the cyst surgically can also affect this reserve. According to the ESHRE 2022 guideline, routine surgery before IVF solely to increase the chance of pregnancy is not recommended. The decision is made individually, based on age, reserve, symptoms and pregnancy plans.

Can an ovarian cyst turn into cancer?

The vast majority of cysts found before the menopause are non-cancerous. The cancer risk of a cyst is assessed from its ultrasound appearance (IOTA rules, O-RADS). After the menopause, cysts are examined more carefully; ultrasound findings and CA-125 are combined to calculate a cancer risk score, and those at high risk are referred to a women's cancer team.

What happens if a cyst bursts?

When the wall of the cyst tears and its contents empty into the abdomen, there can be sudden, severe pain and internal bleeding. If the bleeding continues or the general condition worsens, emergency surgery is needed. With sudden, severe pain in the lower abdomen or belly, go to the emergency department without waiting.

How can twisting of the ovary (torsion) be recognised?

Sudden, severe, doubling-up pain on one side of the lower abdomen or belly, together with nausea and vomiting, is typical. Urgent surgery is needed so that the ovary does not lose its blood supply. In pregnancy, this risk is highest with cysts between 6 and 10 cm and in the first three months.

Does the contraceptive pill dissolve a cyst?

No. Studies and systematic reviews have shown that the contraceptive pill does not speed up the disappearance of existing functional cysts. Because the pill suppresses ovulation, it is effective in preventing new functional cysts from forming.

My CA-125 is high — does that mean cancer?

No, not on its own. Before the menopause, CA-125 can also rise in non-cancerous conditions such as endometriosis, fibroids, infections in the pelvic area and even during a period; for this reason, it is not recommended as a routine test at this stage. After the menopause, it is more useful when assessed together with the ultrasound findings.

Is the ovary removed during cyst surgery?

For cysts that look non-cancerous, the first choice is laparoscopic cystectomy: during keyhole surgery only the cyst is removed by peeling away its wall, and healthy ovarian tissue is preserved. To protect the ovarian reserve, burning the tissue more than necessary is avoided. Simply draining the fluid from the cyst is not recommended, because the cyst comes back in a high proportion of cases.

Is polycystic ovary syndrome the same as an ovarian cyst?

No. In polycystic ovary syndrome (PCOS), many small egg sacs are seen in the ovary on ultrasound; these are not cysts that need treatment. PCOS is a separate condition that affects hormones, the menstrual cycle and metabolism, and it is managed differently from an ovarian cyst.

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